I wanted to spend today’s post letting you know about a couple of hyperemesis gravidarum studies that are going on right now. I would ask that you please consider participating in these studies. Even if you haven’t had HG, you can still participate. The research group actually really needs control subjects who did not have HG to help understand the information gathered from the participants with HG.
Here are the studies:
Current 2007-2015 Study: Genetics of Hyperemesis Gravidarum (HG)
This study is designed to identify individuals affected with HG, to study epidemiologic factors via an online survey, to collect DNA samples from saliva through the mail at no cost or travel for you, and to search for genes and risk factors that may be potentially associated with this condition. To be eligible, you must have suffered from HG and had treatment for your HG that includes i.v. hydration, TPN or other form of non-oral feeding (ie nasogastric feeding), OR both, and are able to recruit a friend with at least 2 pregnancies who has NOT suffered from HG to serve as a control.
You can learn more about the study and register here. The study itself is very easy and painless. After you take a detailed online survey, they will mail you a cheek swab kit so that they can register and analyze your DNA. That’s it. No doctor’s visits. Just a little cheek swab that you take yourself.
2011 HG Survey: survey to determine the effectiveness of medications/treatments for HG
We have also begun a new study to determine medication effectiveness. If you are trying to conceive or newly pregnant and have had HG in a past pregnancy, please consider participating in this study by filling out this short survey as close to your first positive pregnancy test as possible and thereafter to let us know how medications effect your intake and nausea.
These kinds of studies are so critical. The more we know about the root causes of HG, the better treatment we can find. Even though this won’t affect my childbearing years or decisions, I hope that the results of these studies will help my daughters. There’s a strong chance, due to the genetic nature of HG, that one or both of my girls will suffer from this disease. If I can protect them even a little bit from this. I want to. Please consider helping.
Here is a selection of the articles they’ve been able to publish as a result of their studies:
- Risk factors, treatments, and outcomes associated with prolonged hyperemesis gravidarum. http://informahealthcare.com/eprint/UM2GzTh8Cj6sFwWUEC8d/full
- Prenatal exposure to hyperemesis gravidarum linked to increased risk of psychological and behavioral disorders in adulthood. http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8351138
- Posttraumatic stress symptoms following pregnancy complicated by hyperemesis gravidarum. http://www.ncbi.nlm.nih.gov/pubmed/21635201
- Recurrence risk of hyperemesis gravidarum. http://www.ncbi.nlm.nih.gov/pubmed/21429077
- Familial aggregation of hyperemesis gravidarum. http://www.ncbi.nlm.nih.gov/pubmed/20974461
- Symptoms and pregnancy outcomes associated with extreme weight loss among women with hyperemesis gravidarum. http://www.ncbi.nlm.nih.gov/pubmed/20044860
- Patients with a history of hyperemesis gravidarum have similar symptoms during egg stimulation and develop ovarian hyperstimulation syndrome: case series. http://www.ncbi.nlm.nih.gov/pubmed/19878938
- High prevalence of severe nausea and vomiting of pregnancy and hyperemesis gravidarum among relatives of affected individuals. http://www.ncbi.nlm.nih.gov/pubmed/18752885
- Secular trends in the treatment of hyperemesis gravidarum. http://www.ncbi.nlm.nih.gov/pubmed/18260047
- Elective pregnancy termination in a large cohort of women with hyperemesis gravidarum. http://www.ncbi.nlm.nih.gov/pubmed/18061703
- The psychosocial burden of hyperemesis gravidarum. http://www.ncbi.nlm.nih.gov/pubmed/18059463